The international airport of Oaxaca City serves this region. The complex birding route involves an extended circle that requires beginning and ending in the same location.
Endemic MUST-SEE BIRDS of this region include: TOWNSEND'S SHEARWATER, TUXTLA QUAIL-DOVE, GREEN-FRONTED, CINNAMON-SIDED, BLUE-CAPPED, & BEAUTIFUL HUMMINGBIRDS. LONG-TAILED SABREWING, PILEATED & FLAMMULATED FLYCATCHERS, SLATY & DWARF VIREOS, DWARF & WHITE-THROATED JAYS, GRAY-BARRED, GIANT, BOUCARD'S, SUMICHRAST'S, & NAVA'S WRENS, OCELLATED THRASHER, WHITE-NAPED BRUSH-FINCH, COLLARED & WHITE-THORATED TOWHEES, BRIDLED, CINNAMON-TAILED, & OAXACA SPARROWS, AND ROSE BELLIED-BUNTING.
Endemic SHARED-REGION BIRDS also regularly found on this route include: WEST MEXICAN CHACHALACA, LONG-TAILED WOOD-PARTRIDGE, LILAC-CROWNED PARROT, COLIMA PYGMY-OWL, MEXICAN HERMIT, GOLDEN-CROWNED EMERALD, BUMBLEBEE, & DOUBLEDAY'S HUMMINGBIRDS, GOLDEN-CHEEKED, GRAY-BREASTED & GRAY-CROWNED WOODPECKERS, WAGLER'S TOUCANET, CITEROLINE TROGON, WHITE-STRIPED WOODCREEPER, HAPPY WREN, RUSSET NIGHTINGALE-THRUSH, RUFOUS-BACKED ROBIN, AZTEC THURSH, BLUE MOCKINGBIRD, RED WARBLER, HOODED YELLOWTHROAT, RED-BREASTED CHAT, RED-HEADED TANAGER, GODMAN'S EUPHONIA, CINNAMON-RUMPED SEEDEATER, RUFOUS-CAPPED BRUSH-FINCH, ORANGE-BREASTED BUNTING, & DICKEY'S ORIOLE.
Other non-endemic birds of interest better seen in this region include: Thicket Tinamou, Singing Quail, White-faced Quail-Dove, Pheasant Cuckoo, Lesser Ground-Cuckoo, Wagler's Toucanet, Great Swallow-tailed Swift, Blue-throated & Tody Motmots, Garnet-throated & White-striped Hummingbirds, Ruddy Foliage-gleaner, Rufuos-breasted Spinetail, Gray-collared Becard, Chestnut-sided & Green Shrike-Vireos, Black-throated & Unicolored Jays, Banded, White-bellied, & Rufous-browed Wrens, White-lored & Tropical Gnatcatchers, Brown-backed & Slate-colored Solitaires, Pink-headed, Crescent-chested & Fan-tailed Warblers, Black-faced & Yellow Grosbeaks, Ochre [winter] Oriole, Cinnamon-bellied Flowerpiercer, and Plain & Black-capped Siskins.
The strategy for this region uses a counter-clockwise loop that includes:
 the Sierra Madre de Oaxaca,
 the arid Pacific coast & a min-pelagic,
 the Isthmus of Tehuantepec,
 the interior valley of Chiapas at Tuxtla Gutierrez & El Sumidero N.P.,
 the Guatemalan Highlands near San Cristobal,
 a drop in elevation to traverse the Atlantic slope,
 the Caribbean lowlands near Uxpanapa,
 an assent into the Sierra Los Tuxtlas, and a return to Oaxaca City via
 the karst foothills of Tuxtepec, and
 a traverse of the Atlantic slope near Valle Nacional.
It is best run during the breeding season - April through July - as there are over 500 possible species.